Neurocysticercosis in Nepal and it's global perspective.

Before 1990s, reliable data on the prevalence of NCC were limited. Neuro imaging studies, biopsy or autopsy studies needed to confirm the diagnosis, were not easily available in areas where the infection was endemic. Serological assay performed with unfractioned antigens were both insensitive and non-specific.3 Enzymelinked Immuno electrotransfer blot (EITB) was the first specific assay for T. solium infection that could be used in large field studies.1 With the increasing availability of neuroimaging studies in the area of endemicity and the use of EITB assay in epidemiological studies, it has become evident that the global morbidity and mortality associated with cysticercosis have been grossly underestimated.3 Concepts regarding the prevalence of infection, associated morbidity and mortality, treatment and epidemiology have changed dramatically over the past two decades.